Solstice Neurosciences, Inc.’s President & CEO, Shawn Patrick O’Brien Named Ernst & Young Entrepreneur Of The Year^® 2007 Award Finalist In Greater Philadelphia

Malvern, Pennsylvania-June 4, 2007 –Solstice Neurosciences, Inc. (Solstice) today announced that President & CEO Shawn Patrick O’Brien is a finalist for the Ernst & Young Entrepreneur Of The Year^® 2007 Award in the Greater Philadelphia region. According to Ernst & Young, the awards program was designed to recognize outstanding entrepreneurs on a regional, national and global level who are building and leading dynamic, growing businesses. Shawn O’Brien was selected as a finalist from nearly 75 nominations by a panel of independent judges. Award winners will be announced at a special gala event on June 21, 2007, at the Philadelphia Loews Hotel.

“To me, becoming a finalist in the Ernst & Young Entrepreneur Of The Year award is truly a reflection of the Solstice employees and the entrepreneurial spirit that they embrace. For a small, young biopharmaceutical company, Solstice has achieved some substantial business accomplishments, yet, we stay true to our vision to help patients significantly improve the quality of their lives” commented Mr. O’Brien. “Having created over 150 jobs in a 3-year time frame, we have more people and more creative resources available to continue to develop steadfast relationships with our customers. All of us here at Solstice foster the spirit of seeing things that others don’t envision, and doing the work others are not willing to do.”

The Ernst & Young Entrepreneur Of The Year awards program celebrates its 21st anniversary this year. Awards are given to entrepreneurs who have demonstrated excellence and extraordinary success in such areas as innovation, financial performance, and personal commitment to their businesses and communities.

Regional award winners are eligible for consideration for the Ernst & Young Entrepreneur Of The Year 2007 national program. Award winners in several national categories, as well as the overall national Ernst & Young Entrepreneur Of The Year award winner, will be announced at the annual awards gala in Palm Springs, California on November 17, 2007. The national Entrepreneur Of The Year celebration is part of Ernst & Young’s Strategic Growth Forum. The overall national Entrepreneur of the Year award recipient is then considered for the world event held in Monte Carlo.

Sponsors

Founded and produced by Ernst & Young LLP, the Entrepreneur Of The Year Awards are pleased to have Bank of America as the national presenting sponsor, as well as SAP America and the Ewing Marion Kauffman Foundation as national sponsors. In Greater Philadelphia, local sponsors include Marsh, Ballard Spahr, Pepper Hamilton and Morgan Lewis Bockius LLP.

Founded in 2004, Solstice Neurosciences, Inc. is a biopharmaceutical company focused on the development, manufacturing, sales and marketing of specialty products. Solstice’s first product, Myobloc^® (Botulinum Toxin Type B) Injectable Solution 5,000U/mL, represents the only botulinum toxin type B currently available to physicians and patients worldwide. MYOBLOC is sold in the United States and approved in Canada. It is also sold and distributed in Europe as NeuroBloc^®. MYOBLOC is indicated for the treatment of patients with cervical dystonia (CD) to reduce the severity of abnormal head position and pain associated with CD. For more information about Solstice Neurosciences, Inc., visit www.solsticeneuro.com

The Entrepreneur Of The Year^® awards program was created and is produced by professional services firm Ernst & Young LLP. As the first award of its kind, the Ernst & Young Entrepreneur Of The Year^® award recognizes outstanding entrepreneurs who are building and leading dynamic and growing businesses. The program, which celebrated its 20th anniversary in 2006, honors entrepreneurs through regional, national and global award programs in over 125 cities and 40 countries.

Ernst & Young, a global leader in professional services, is committed to enhancing the public’s trust in professional services firms and in the quality of financial reporting. Its 114,000 people in 140 countries pursue the highest levels of integrity, quality, and professionalism in providing a range of sophisticated services centered on our core competencies of auditing, accounting, tax, and transactions. Further information about Ernst & Young and its approach to a variety of business issues can be found at www.ey.com/perspectives. Ernst & Young refers to the global organization of member firms of Ernst & Young Global Limited, a U.K. company limited by guarantee, each of which is a separate legal entity. Ernst & Young Global Limited does not provide services to clients. Ernst & Young LLP is a U.S. client-serving member firm of Ernst & Young Global Limited.

Contacts

Diane Murray, Director–Business Operations & Communications

Phone: Toll Free (866) 220-5042, or Direct (610) 864-1691

Email: diane.murray@solsticeneuro.com

Myobloc^® and NeuroBloc^® are registered trademarks of Solstice Neurosciences, Inc.